You are here: Home » Recipes » Four-Cheese Macaroni and Cheese Four-Cheese Macaroni and Cheese Recipe by RelishKitchen Tested Yield 8 servings Prep 15 mins Cook 40 mins America's favorite pasta dish with four cheeses. Mark Boughton Photography / styling: Teresa Blackburn PrintEmail Ingredients 3 cups uncooked penne pasta1 large egg2 cloves garlic, minced1 1/2 cups 2% low-fat milk1 cup (4 ounces) shredded sharp Cheddar cheese4 ounces cream cheese1 cup (4 ounces) shredded Gruyère or Swiss cheese3/4 cup (3 ounces) grated Parmigiano-Reggiano cheese1/8 teaspoon red pepper flakes1/8 teaspoon salt1/8 teaspoon pepper3 tablespoons butter12 saltine crackers, crumbled Instructions Cook pasta according to package directions, drain. Preheat oven to 350F. Lightly grease a 13 x 9-inch or 8-cup casserole dish. Combine egg, garlic and milk and mix well. Place pasta in a large casserole dish. Add milk mixture and remaining ingredients, except butter and crackers. Mix well with a spoon. Combine butter and crackers. Sprinkle over pasta. Bake 30 minutes or until browned and bubbly.